Lateral Wall Ischemia

Blockage in the heart's Circumflex, or "left side" artery

Case History:

 

This 48 year old diabetic man noted increasing shortness of breath with activities.  He denied symptoms of chest discomfort.  His Type I diabetes was longstanding, and complicated by kidney dysfunction.

 

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Dual-isotope perfusion imaging using Technetium-99m Sestamibi and thallium tracers shows a large reversible perfusion defect in the anterolateral and inferolateral walls (red arrows).     This defect is present during stress (the 1st, 3rd and 5th rows from top- white bars at left) and resolves with rest (see the 2nd, 4th and 6th rows-- red bars at left).  Careful inspection also reveals reversible perfusion defects in the inferior (bottom) wall as well as portions of the anterior (top) wall.  Reversible defects indicate ischemia, or a reduction of blood flow with increasing metabolic demands.    

Cardiac Catheterization was performed, showing severe stenoses (blockages) in all three major coronary arteries.  The circumflex, or side, artery was the most severely narrowed.  Also, the Left Anterior Descending and the Right Coronary Artery were significantly affected.   He underwent uneventful three vessel coronary artery bypass surgery.  Ventricular (heart muscle) function was normal after the surgery, suggesting that no permanent injury had occurred. 

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